You may also need frequent medical tests. The dose may be taken by mouth once per day, or twice a day in two equal doses. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking. If blood pressure is not controlled by candesartan cilexetil tablets alone, a diuretic may be added. Candesartan is also used in adults with certain types of heart failure, to reduce serious complications or death due to heart damage. A normal adult dose may cause levels of this drug to be higher than normal. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. It may take up to 4 weeks before your blood pressure is under control. Your doctor may increase your dosage to a maximum of 32 mg per day. You may have increased shortness of breath, chest pain, more fatigue, and irregular heart rate. This is not a complete list of side effects and others may occur. Common side effects of candesartan include back pain, dizziness, and cold- or flu-like symptoms such as sore throat and nasal congestion. Stopping the drug suddenly can cause your blood pressure to get higher. You may report side effects to FDA at 1-800-FDA-1088. Your blood pressure may get worse. However, the effect of long-term hyperuricemia on cardiac and renal outcomes remains controversial. As a treatment for high blood pressure, this drug hasn’t been studied in very young children. If you become pregnant, stop taking candesartan and tell your doctor right away. The patient was hesitant to retry a diuretic, but was persuaded to take hydrochlorothiazide 12.5 mg daily, subsequently advanced to 25 mg daily. It also improves your survival if you're taking it for heart failure. Hydrochlorothiazide is a thiazide diuretic (water pill). Not all possible drug interactions are listed here. Heart failure: Use caution when initiating in heart failure; may need to adjust dose, and/or concurrent diuretic therapy, because of candesartan-induced hypotension. That means two things: You shouldn’t take candesartan if you’re pregnant. Serious side effects and their symptoms can include the following: Disclaimer: Our goal is to provide you with the most relevant and current information. Candesartan is a long-term drug treatment. All possible dosages and forms may not be included here. This drug has a black box warning. Common Blood Pressure Meds Won't Up Risks for COVID-19 Patients: Study. This combination medication is used to lower high blood pressure.Candesartan works by relaxing blood vessels. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. Healthline Media does not provide medical advice, diagnosis, or treatment. Other drugs may affect candesartan, including prescription and over-the-counter medicines, vitamins, and herbal products. Keep your drugs away from areas where they could get damp or wet, such as bathrooms. Copyright 1996-2021 Cerner Multum, Inc. Description: Candesartan is a prodrug of candesartan cilexetil that blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin II by selectively binding to AT 1 receptors. Version: 8.01. amlodipine, lisinopril, metoprolol, losartan, furosemide, hydrochlorothiazide, carvedilol, spironolactone. You may have very low blood pressure while taking this medication. At randomization and after 24 weeks, systolic and diastolic BP, … If you’re taking candesartan for heart failure, your heart failure may get worse. The bran… Medically reviewed by Drugs.com on Dec 25, 2020. Taking it a second time after an allergic reaction could be fatal. This information is not a substitute for medical advice. Don’t worry about airport X-ray machines. For children: Use of this drug in children depends on treatment. We look at what research and medical professionals had to say about mattresses improving sleep and what to keep in mind. Never try to catch up by taking two doses at once. For people with diabetes: If you have diabetes and are taking aliskiren, you shouldn’t take candesartan. angiotensin receptor blockers (ARBs), such as: angiotensin-converting enzyme (ACE) inhibitors, such as: Studies show a risk of adverse effects to the fetus when the mother takes the drug. Don’t take candesartan if you’re pregnant. Available for Android and iOS devices. 2.2 Pediatric Hypertension 1 to < 17 Years of Age . Stop using candesartan and tell your doctor right away if you become pregnant. Several studies have shown that hyperuricemia is a risk fact… Call your doctor right away if you have serious side effects. Candesartan cilexetil, a nonpeptide, is chemically described as (±)-1-Hydroxyethyl 2-ethoxy-1-[ p -( o -1 H -tetrazol-5-ylphenyl)benzyl]-7-benzimidazolecarboxylate, cyclohexyl carbonate (ester). Select one or more newsletters to continue. Always carry it with you in your carry-on bag. The combination of an ACE inhibitor, a potassium-sparing diuretic (e.g. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. 4 mg taken by mouth once per day. Candesartan oral tablet does not cause drowsiness, but it can cause other side effects. Do not use if you are pregnant. Candesartan helps to prevent future strokes, heart attacks and kidney problems. Initial dose: 16 mg orally once a dayMaintenance dose: 8 to 32 mg/day orally in 1 to 2 divided dosesMaximum dose: 32 mg/dayComments:-Consider administration of a lower initial dose in volume depleted patients.-Most of the antihypertensive effect is present within 2 weeks; maximum blood pressure reduction at a given dose is generally observed within 4 to 6 weeks of starting that dose. HCTZ is a thiazide diuretic that acts by interfering with the reabsorption of sodium ions from renal tubules. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Monitoring of serum creatinine is recommended during dose It shouldn’t be used in people younger than 18 years for this purpose. Candesartan is an angiotensin II receptor antagonist. It shouldn’t be used in children younger than 1 year. Candesartan is an oral drug used to treat high blood pressure and heart failure. Usual Adult Dose for Congestive Heart Failure: Initial dose: 4 mg orally once a day; double dose every 2 weeks, as tolerated, to target dose of 32 mg orally once a dayUse: Treatment of New York Heart Association (NYHA) class II through IV heart failure. This is the most serious warning from the Food and Drug Administration (FDA). People with serious mental health conditions are at higher risk of developing COVID-19. Most Americans Can't, 4 Hidden Habits That May Affect Your Blood Pressure. Candesartan can be administered with other heart failure treatment, including ACE-inhibitors, beta-blockers, diuretics and digitalis or a combination of these medicinal products. Those diagnosed with…, The American Heart Association released a list of hidden habits that can impact a person's blood pressure. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Its empirical formula is C 33 H 34 N 6 O 6, and its structural formula is You may need to use blood pressure medicine for the rest of your life. § Hyperkalemia: Concomitant use of candesartan with potassium-sparing diuretics, potassium supplements, salt substitutes containing potassium or other drugs that may increase potassium levels (e.g., heparin) may lead to increases in serum potassium in If you think that you’ve taken too much candesartan, call your doctor or local poison control center, or go to the emergency room right away. However, a combination formulation exists with low-dose hydrochlorothiazide, a thiazide diuretic. If you forget to take your dose, take it as soon as you remember. We comply with the HONcode standard for trustworthy health information -, Drug class: angiotensin receptor blockers. You may take candesartan with or without food. A 34-year-old member asked: In some cases, they may not be available in every strength or form as the brand-name version. For pregnant women: Candesartan is a category D pregnancy drug. Your dose, form, and how often you take it will depend on: This drug hasn’t been studied in very young children. You may have a higher chance of a heart attack or stroke. Candesartan is used to treat high blood pressure (hypertension) in adults and children who are at least 1 year old. As a result, candesartan relaxes the blood vessels. cold symptoms such as stuffy nose, sneezing, sore throat. Data sources include IBM Watson Micromedex (updated 2 Feb 2021), Cerner Multum™ (updated 3 Feb 2021), ASHP (updated 29 Jan 2021) and others. Candesartan cilexetil, a nonpeptide, is chemically described as (±)-1-Hydroxyethyl 2-ethoxy-1- [p- (o- 1H-tetrazol-5-ylphenyl)benzyl]-7-benzimidazolecarboxylate, cyclohexyl carbonate (ester). These medicines help the kidney to get rid of excess fluid from the body. Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention. That way, a pharmacist can check for possible drug interactions. During your treatment with candesartan, your doctor may monitor your: Many insurance companies require a prior authorization for this drug. If you are taking a salt substitute that has potassium in it, a potassium-sparing diuretic, or a potassium product, talk with your doctor. Hydrochlorothiazide belongs to a family of medications known as diuretics (or \"water pills\"). Taking these medications with candesartan can increase your potassium levels. If you have high blood pressure, keep using this medicine even if you feel well. Examples of these drugs include: Taking these medications with candesartan raise your risk of very low blood pressure, high blood potassium levels, and worsened kidney function. For people with kidney problems: This drug can make your kidney problems worse. Keep these considerations in mind if your doctor prescribes candesartan for you. If they’re more severe or don’t go away, talk to your doctor or pharmacist. A comes in various doses and each strenght has a 12.5 and 25 mg dose of hydrochlorthiazide added to if, it the physician choses to prescribe it. kidney problems--little or no urination, swelling in your feet or ankles, feeling tired or short of breath. For women who are breastfeeding: It isn’t known if candesartan passes into breast milk. You should not use this medication if you are allergic to candesartan. Candesartan is often prescribed as monotherapy for the management of hypertension and heart failure. You shouldn’t stop taking candesartan without talking to your doctor. During treatment with candesartan cilexetil in patients with heart failure, periodic monitoring of serum potassium is recommended, especially when taken concomitantly with ACE inhibitors and potassium-sparing diuretics such asspironolactone. Generic drugs usually cost less. The total daily dose can range from 8–32 mg taken in 1 or 2 divided doses. This drug is not available as an oral suspension, but your pharmacist may be able to prepare it for you. Candesartan works by relaxing the blood vessels in your body. It shouldn’t be used to treat high blood pressure in children younger than 1 year. Bring this diary with you to your doctor appointments. Do not use potassium supplements or salt substitutes, unless your doctor has told you to. Our website services, content, and products are for informational purposes only. The CROSS (Candesartan Role on Obesity and on Sympathetic System) study was undertaken to examine the antihypertensive, neuroadrenergic, and metabolic effects of an angiotensin II receptor blocker in comparison with a diuretic in obese hypertensive individuals. As with other angiotensin II receptor antagonists, candesartan is indicated for the treatment of hypertension. Candesartan oral tablet can interact with other medications, herbs, or vitamins you might be taking. Debra Sullivan, Ph.D., MSN, R.N., CNE, COI, People With Mental Health Conditions Are at High Risk for COVID-19, So Why Aren't They Being Prioritized. For seniors: Older adults may process drugs more slowly. This raises your risk of a heart attack or stroke. This lowers blood pressure and increases the supply of blood and oxygen to the heart. There are other drugs available to treat your condition. This can cause more side effects. Candesartan is also used in adults with certain types of heart failure, to reduce serious complications or death due to heart damage. spironolactone) and Candesartan Cilexetil is not recommended and should be considered only after careful evaluation of the potential benefits and risks. This combination product contains 2 medications: candesartan and hydrochlorothiazide. Older adults may process drugs more slowly. It comes as an oral tablet. Candesartan is used to treat high blood pressure and heart failure. Candesartan can cause injury or death to the unborn baby if you take the medicine during your second or third trimester. Case 2: A 43‐year‐old man was seen in our hypertension clinic because of uncontrolled BP. Patients with hypertension and serum uric acid > or = 0.42 mmol/L (7 mg/dL) associated with diuretics were randomized to receive losartan 50 to 100 mg or candesartan 8 to 16 mg for 24 weeks. If you need surgery, tell the surgeon ahead of time that you are using candesartan. Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Candesartan is available as both a generic and brand-name drug. This medicine is only available on prescription. Candesartan belongs to a class of drugs called angiotensin receptor blockers (ARBs). Keep a log with the date, time of day, and your blood pressure readings. Angiotensin II is a chemical that the body releases to cause the constriction (tightening up) of blood vessels. It reduces the amount of water in the body by increasing the … This could cause toxic side effects. The Candesartan Antihypertensive Survival Evaluation in Japan Trial was designed to compare the long-term effects of the angiotensin II receptor blocker candesartan and the calcium channel blocker amlodipine on the incidence of cardiovascular events, represented as a composite of sudden death and cerebrovascular, cardiac, renal, and vascular events in high-risk Japanese hypertensive patients. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Candesartan cilexetil (candesartan) is a drug used for treating high blood pressure (hypertension). a light-headed feeling, like you might pass out; high potassium level--nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement; or. Hepatic impairment: Systemic exposure increases in hepatic impairment. There are no specific recommendations for senior dosing. Initially 4 mg daily. Last medically reviewed on March 25, 2016. This information is not a substitute for medical advice. It belongs to a Does a Good Mattress Lead to Better Sleep? kidney disease (or if you are on dialysis); Do not use if you are pregnant. Tell your doctor about all your other medicines, especially: NSAIDs (nonsteroidal anti-inflammatory drugs)--ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. © 2005-2021 Healthline Media a Red Ventures Company. Your symptoms of heart failure may get worse. Use with caution if eGFR less than 15 mL/minute/1.73 m 2 —limited experience. Candesartan has many different effects on your body and is used to treat a variety of conditions. This helps reduce your blood pressure and lowers your chance of having a stroke or heart attack. Heart Failure: In heart failure patients, increases in serum creatinine may occur. Your blood pressure will need to be checked often. Candesartan keeps blood vessels from narrowing, which lowers blood pressure and … Your symptoms of heart failure, such as shortness of breath, irregular heart rate, chest pain, and fatigue may also get worse. It’s also available as a generic drug. You or your pharmacy will have to contact your doctor for a new prescription if you need this medication refilled. Lowering blood pressure can reduce the risk of stroke, heart attack, or other heart complications. increase the dose to 32 mg once a day if your blood pressure has not decreased enough Candesartan is a prescription drug. But they still aren't being prioritized for vaccination. If it does, it may cause serious effects in a child who is breastfed. For CANDESARTAN CILEXETIL. They can’t hurt this medication. Keep the original prescription label with you when traveling. Store candesartan at room temperature below 86°F (30°C). If you’re taking this drug for heart failure, you may be able to tell this drug is working if your symptoms, such as shortness of breath, chest pain, cough, and fatigue, get better. Examples of drugs that can cause interactions with candesartan are listed below. Tell all of your health care providers and lab workers that you take candesartan and hydrochlorothiazide. This information is not a substitute for medical advice. This drug hasn’t been studied in children for treatment of heart failure. Candesartan is the genic name, the name of the active drug found in the medication, but it is also known by the brand name: Atacand.There are four different doses: 4 mg, 8 mg, 16 mg and 32 mg. You will probably start taking a low dose of 4 mg, to reduce the risk of side effects as your body gets used to the new medication. You can also check your blood pressure at home. Examples of these drugs include: Disclaimer: Our goal is to provide you with the most relevant and current information. If you get pregnant or plan to become pregnant, call your doctor right away. Tell your doctor if you’re pregnant or plan to become pregnant. As a treatment for heart failure, this drug hasn’t been studied in children. Store at room temperature away from moisture and heat. Your blood pressure may not improve and may get worse. Note: You can reduce your chances of drug interactions by having all of your prescriptions filled at the same pharmacy. Follow‐up BPs were 128 to 132 mm Hg/66 to 72 mm Hg without recurrence of gout 6 months later. Tell the doctor if a child taking this medicine has trouble swallowing the tablet. If it’s just a few hours until the time for your next dose, then wait and only take one dose at that time. A class of drugs refers to medications that work similarly. Candesartan may not work as well to decrease blood pressure when it’s taken with non-steroidal anti-inflammatory drugs (NSAIDs). A comes in various doses and each strenght has a 12.5 and 25 mg dose of hyd ... Read More. Chances are, the sleep crust in your eyes is perfectly normal and part of your eyes' self-cleaning system. Call your doctor if you are sick with vomiting or diarrhea, or if you are sweating more than usual. Hydrochlorothiazide is a diuretic acting mainly in at the beginning of the distal tubules. Dose adjustments. It may cause birth defects or be fatal to your unborn baby. In heart failure patients treated with candesartan cilexetil, hyperkalaemia may occur. Fighting high blood pressure or…. The benefits of taking the drug during pregnancy may outweigh the potential risks in certain cases. Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. That’s why your doctor should manage all of your medications carefully. Candesartan may also be used for purposes not listed in this medication guide. Children who weigh less than 50 kg: The recommended starting dosage is 4, Children who weigh 50 kg or more: The recommended starting dosage is 8–16 mg per day. Thus, the diuresis induced is not associated with increased GFR and may exacerbate the situation if hypovolaemia is a significant contributory cause, potentially to a critical level such that the autoregulatory mechanisms can no longer compensate. You may need to show your pharmacy’s label to clearly identify the medication. If you’re a senior, taking water pills, are dehydrated, or have a history of kidney problems, your kidney function may get worse if you take these drugs together. Candesartan is an oral drug used to treat high blood pressure and heart failure. Atacand (candesartan) and diuretic: Yes, Atacand (candesartan) (a) can have, and is marketed, with a diuretic. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. take other medications that affect your blood pressure, cold- or flu-like symptoms, such as fever, cough, sneezing, and a runny nose. It may cause very low blood pressure. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. Candesartan belongs to a family of medications known as angiotensin II receptor blockers. Some may be more suitable for you than others. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Candesartan/hydrochlorothiazide combination preparations are marketed under various trade names including Atacand HCT, Hytacand, Blopress Plus, Advantec and Ratacand Plus. You may also need to avoid taking candesartan with aliskiren if you have kidney disease. Your doctor will monitor your blood pressure at your checkups. Hyperuricemia is common in patients with essential hypertension.1 Diuretics are the preferred first-line therapy for uncomplicated essential hypertension,2 but may cause hyperuricemia or exacerbate pre-existing hyperuricemia.3,4 Untreated hyperuricemia may predispose to gout, leading to poor patient compliance or withdrawal of diuretic therapy. If you’re a senior, you may need a lower dose or a different schedule. When used to treat heart failure, candesartan is almost always used with other medicines called diuretics or fluid tablets. High blood pressure often has no symptoms. Candesartan is a medicine widely used to treat high blood pressure (hypertension) and heart failure. That means you need to take it with other drugs. Send thanks to the doctor. Mechanism of Action Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Brand name (s): Atacand. Here’s a breakdown of what Zenni Optical has to offer if you're looking to take the headache out of shopping for eyeglasses. This drug may be used as part of a combination therapy. Candesartan is available as the brand-name drug Atacand. Stopping the drug suddenly may also worsen your symptoms of heart failure. Heart failure can even be fatal. You can then gradually increase the dose as needed to manage blood pressure.Candesartan is also available in combination with another drug, hydrochlorothiazide.